The pressure difference of the bag filter is an important parameter affecting its stable operation, and the pressure difference should be controlled within 1 500Pa. Taking the pressure difference control of low-pressure pulse bag filter in a refining furnace of a steel plant as an example, this paper analyzes the mechanical resistance and dust layer resistance as the main factors for the increase of the pressure difference of the filter through the simple resistance formula, and further analyzes the reasons for the increase of the pressure difference of the bag filter in the early stage of operation and in the process of use. By optimizing the air volume distribution of the dust removal point, adding interlocking control, reducing the filtration velocity, strengthening the dust removal mode and upgrading the filter material transformation and other technical improvement measures, the pressure difference of the dust collector is stable at ≤1 500Pa, the dust emission concentration is ≤10mg/Nm3, the dust collector is stable and efficient, and it also meets the requirements of ultra-low emission.